Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941576 | 0.90 | ALOX5 (0.48) | ALOX5CA1CA2LMNANPC1 | |
| SCHEMBL8941420 | 0.88 | MIF (0.38) | ALOX5CA1CA2LMNANPC1 | |
| SCHEMBL8941438 | 0.88 | POLB (0.50) | LMNAALDH1A1NPC1POLBRAB9A | |
| SCHEMBL8941751 | 0.87 | ALOX5 (0.53) | ALOX5LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8941414 | 0.86 | F10 (0.42) | ALOX5LMNAALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8941440 | 0.84 | HTT (0.47) | ALOX5NPC1POLB | |
| SCHEMBL6896344 | 0.76 | CA1 (0.48) | CA1CA2LMNAALDH1A1NPC1 | |
| SCHEMBL21066088 | 0.76 | CA1 (0.46) | CA1CA2PKM | |
| SCHEMBL3989205 | 0.71 | CA1 (0.69) | CA1CA2LMNAALDH1A1NPC1 | |
| SCHEMBL17321472 | 0.70 | CA1 (0.62) | CA1CA2LMNANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |