Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941641 | 0.87 | PTPRZ1 (0.50) | PTPRZ1HSD11B1SMN1; SMN2HTTLMNA | |
| SCHEMBL8941594 | 0.87 | PTPRZ1 (0.50) | NR3C2PTPRZ1HSD11B1SMN1; SMN2HTT | |
| SCHEMBL8941680 | 0.82 | PTGS2 (0.46) | HSD11B1SMN1; SMN2HTTLMNASOS1 | |
| SCHEMBL5670628 | 0.78 | LMNA (0.47) | PTPRZ1HSD11B1SMN1; SMN2HTTLMNA | |
| SCHEMBL8941539 | 0.77 | NR3C2 (0.54) | NR3C2SMN1; SMN2HTTLMNAALDH1A1 | |
| Sulfuric Acid SCHEMBL29687373 | 0.77 | NR3C2 (0.53) | NR3C2SMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL11507063 | 0.76 | PTPRZ1 (0.61) | PTPRZ1SMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL8941531 | 0.75 | PTPRZ1 (0.50) | PTPRZ1SMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL8941634 | 0.75 | HTT (0.57) | PTPRZ1HSD11B1SMN1; SMN2HTTLMNA | |
| SCHEMBL3020464 | 0.75 | HTT (0.62) | NR3C2HSD11B1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |