Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941539 | 0.83 | NR3C2 (0.54) | PTGS2HTTLMNASMN1; SMN2SOS1 | |
| SCHEMBL8941509 | 0.82 | NR3C2 (0.44) | HTTLMNASMN1; SMN2SOS1PGR | |
| SCHEMBL7990329 | 0.80 | PTGS2 (0.57) | PTGS2KIF11PTGS1CYP11B1CYP11B2 | |
| SCHEMBL757765 | 0.80 | LTA4H (0.52) | SOS1ESR2 | |
| SCHEMBL7359540 | 0.80 | SOS1 (0.64) | PTGS2HTTLMNASMN1; SMN2SOS1 | |
| SCHEMBL10052278 | 0.78 | HSD11B1 (0.51) | HTTSMN1; SMN2SOS1PGRNR3C1 | |
| SCHEMBL8941641 | 0.78 | PTPRZ1 (0.50) | HTTLMNASMN1; SMN2SOS1KIF11 | |
| SCHEMBL7938542 | 0.77 | PTGS2 (0.51) | PTGS2PTGS1HSD11B1 | |
| SCHEMBL21888606 | 0.77 | KIF11 (0.45) | KIF11PGRNR3C1ARESR2 | |
| SCHEMBL822939 | 0.77 | HTT (0.61) | HTTLMNASMN1; SMN2PTGS1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |