Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | SDHB | P21912 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941664 | 0.88 | NR3C1 (0.53) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL8941551 | 0.83 | PTGS2 (0.54) | ALDH1A1KDM4ELMNAPGRPTGS1 | |
| SCHEMBL8773158 | 0.83 | MAPT (0.65) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL29607042 | 0.83 | MAPT (0.65) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL8507695 | 0.81 | MAPT (0.56) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL31287948 | 0.80 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL8669831 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ENTRK1NPSR1 | |
| SCHEMBL8665226 | 0.79 | SDHB (0.58) | MAPTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL30702473 | 0.78 | NR3C1 (0.54) | MAPTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL8855050 | 0.78 | NR3C1 (0.57) | ALDH1A1KDM4ENPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |