Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783039 | 0.81 | TDP1 (0.49) | L3MBTL1TDP1ATMPBRM1CTSL | |
| SCHEMBL8942753 | 0.79 | PARP1 (0.52) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8942623 | 0.79 | HPGD (0.46) | CTSLALDH1A1HPGD | |
| SCHEMBL8942585 | 0.77 | MEN1 (0.42) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8942484 | 0.76 | PARP10 (0.50) | ATMCA1CA2MEN1KMT2A | |
| SCHEMBL8942402 | 0.75 | EPOR (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL8942429 | 0.74 | PARP10 (0.45) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL8942408 | 0.74 | TNKS (0.39) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8942712 | 0.74 | PARP14 (0.45) | MEN1KMT2A | |
| SCHEMBL8942628 | 0.74 | SCN7A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |