Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942753 | 0.88 | PARP1 (0.52) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL8942395 | 0.88 | ALOX5 (0.47) | ALDH1A1ALOX5EPHX2 | |
| SCHEMBL8783388 | 0.83 | ALOX5 (0.48) | MEN1KMT2AGAASMN1; SMN2NPC1 | |
| SCHEMBL8942429 | 0.82 | PARP10 (0.45) | MEN1KMT2AALDH1A1LMNAPARP10 | |
| SCHEMBL8942260 | 0.81 | FURIN (0.39) | KMT2AHTTSMN1; SMN2ALDH1A1F10 | |
| SCHEMBL8942408 | 0.80 | TNKS (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8942712 | 0.80 | PARP14 (0.45) | MEN1KMT2APARP10EPHX2 | |
| SCHEMBL8942679 | 0.80 | MAPT (0.47) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8942661 | 0.79 | KMO (0.53) | MEN1KMT2AALDH1A1PARP10 | |
| SCHEMBL8942507 | 0.78 | KDM4E (0.43) | GAAALDH1A1KDM4EPRSS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |