Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942712 | 0.91 | PARP14 (0.45) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8942661 | 0.88 | KMO (0.53) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8783058 | 0.84 | MEN1 (0.46) | MEN1KMT2AMAPTSNCANPSR1 | |
| SCHEMBL8942429 | 0.84 | PARP10 (0.45) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8942507 | 0.82 | KDM4E (0.43) | MAPTALDH1A1MRGPRX4 | |
| SCHEMBL8942753 | 0.82 | PARP1 (0.52) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL8942679 | 0.81 | MAPT (0.47) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8942402 | 0.81 | EPOR (0.46) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8942585 | 0.80 | MEN1 (0.42) | PARP10MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8942628 | 0.79 | SCN7A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |