Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942753 | 0.92 | PARP1 (0.52) | PARP1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL8942712 | 0.89 | PARP14 (0.45) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL8942679 | 0.88 | MAPT (0.47) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL8942661 | 0.85 | KMO (0.53) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL8942653 | 0.84 | CA1 (0.47) | PARP10PARP2PARP1MTNR1AMTNR1B | |
| SCHEMBL8942408 | 0.84 | TNKS (0.39) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL8782791 | 0.84 | GAA (0.51) | ALDH1A1PGRMEN1KMT2AAR | |
| SCHEMBL8942402 | 0.83 | EPOR (0.46) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL8942585 | 0.82 | MEN1 (0.42) | PARP10PARP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8942507 | 0.82 | KDM4E (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |