Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942429 | 0.92 | PARP10 (0.45) | PARP1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8942585 | 0.88 | MEN1 (0.42) | PARP1MEN1KMT2AGAAPRSS1 | |
| SCHEMBL8942653 | 0.84 | CA1 (0.47) | PARP1MTNR1AMTNR1BCES2CES1 | |
| SCHEMBL8942260 | 0.83 | FURIN (0.39) | MTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL8942395 | 0.83 | ALOX5 (0.47) | ALDH1A1 | |
| SCHEMBL8942408 | 0.82 | TNKS (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8942712 | 0.82 | PARP14 (0.45) | MEN1KMT2A | |
| SCHEMBL8783271 | 0.82 | SIGMAR1 (0.57) | PARP1MEN1KMT2AGAAHPGD | |
| SCHEMBL8942679 | 0.82 | MAPT (0.47) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL8942661 | 0.81 | KMO (0.53) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |