Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.43 |
| ▸ | LOX | P28300 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782555 | 0.85 | LOXL2 (0.52) | SCN7AKCNH2LOXL2LOXF10 | |
| SCHEMBL8942753 | 0.79 | PARP1 (0.52) | — | |
| SCHEMBL8942408 | 0.79 | TNKS (0.39) | — | |
| SCHEMBL8942429 | 0.79 | PARP10 (0.45) | — | |
| SCHEMBL8942712 | 0.79 | PARP14 (0.45) | PPARG | |
| SCHEMBL8942661 | 0.78 | KMO (0.53) | KCNH2 | |
| SCHEMBL8942402 | 0.78 | EPOR (0.46) | — | |
| SCHEMBL8942585 | 0.78 | MEN1 (0.42) | F10F2 | |
| SCHEMBL8942507 | 0.77 | KDM4E (0.43) | PPARGF10 | |
| SCHEMBL8942679 | 0.77 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |