Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782856 | 0.84 | NPC1 (0.49) | KDM4EVEGFAEGLN1NPC1RAB9A | |
| SCHEMBL8942382 | 0.76 | CYP2C9 (0.47) | KDM4ECYP2C9CYP2C19NPC1LMNA | |
| SCHEMBL8942396 | 0.71 | VEGFA (0.57) | KDM4EVEGFAEGLN1NPC1RAB9A | |
| SCHEMBL8942383 | 0.70 | ALDH1A1 (0.45) | KDM4ECYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL31590800 | 0.70 | VEGFA (0.55) | KDM4EVEGFAEGLN1NPC1RAB9A | |
| SCHEMBL12803579 | 0.69 | VEGFA (0.51) | KDM4EVEGFAEGLN1NPC1RAB9A | |
| SCHEMBL7186933 | 0.67 | FEN1 (0.51) | KDM4EVEGFAEGLN1NPC1RAB9A | |
| SCHEMBL8942712 | 0.67 | PARP14 (0.45) | MEN1KMT2AEPHX2 | |
| SCHEMBL8942817 | 0.66 | GAA (0.42) | KDM4ERAB9AMEN1MAPTKMT2A | |
| SCHEMBL8581580 | 0.66 | IDO1 (0.68) | CYP2C9CYP2C19NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |