Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927454 | 0.79 | F2 (0.49) | ALDH1A1HTTF2PRSS1PRSS2 | |
| SCHEMBL6825950 | 0.72 | NPC1 (0.52) | ALDH1A1HTTF2PRSS1PRSS2 | |
| SCHEMBL8783320 | 0.71 | ALDH1A1 (0.59) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4926920 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HTTF2PRSS1PRSS2 | |
| SCHEMBL3267161 | 0.69 | F2 (0.62) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6198665 | 0.68 | CES2 (0.54) | ALDH1A1HTTKDM4ELMNACA2 | |
| Urea SCHEMBL8830202 | 0.67 | LMNA (0.60) | ALDH1A1HTTF2PRSS1PRSS2 | |
| SCHEMBL7371174 | 0.67 | ALDH1A1 (0.68) | ALDH1A1HTTF2PRSS1PRSS2 | |
| SCHEMBL7987098 | 0.67 | NPC1 (0.46) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL20021985 | 0.66 | SLC6A2 (0.60) | ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |