SCHEMBL8943740

SCHEMBL8943740

CCc1ccc(N(c2ccc(CC)cc2)c2ccc(Sc3ccc(N(c4ccc(CC)cc4)c4ccc(CC)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 2/20 0.39
LMNA P02545 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
SLC6A4 P31645 1/20 0.37
CYP2A6 P11509 1/20 0.37
IDO1 P14902 2/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.34
CA2 P00918 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18159470 0.88 TP53 (0.48) LPLLIPGTSHRMAPK1TDP1
SCHEMBL576175 0.88 TP53 (0.48) LPLLIPGTSHRMAPK1TDP1
SCHEMBL12304289 0.85 LPL (0.52) LPLLIPGTSHRMAPK1TDP1
SCHEMBL3896543 0.85 LPL (0.52) LPLLIPGTSHRMAPK1TDP1
SCHEMBL16933906 0.81 EGFR (0.42) LPLLIPGTP53LMNARXFP1
SCHEMBL15500070 0.79 MLYCD (0.42) TDP1L3MBTL1TP53LMNARXFP1
SCHEMBL415478 0.79 TP53 (0.59) TP53LMNARXFP1TAAR1SLC6A4
SCHEMBL10062463 0.78 HRH3 (0.46) LPLLIPGTSHRMAPK1TDP1
SCHEMBL919282 0.78 HRH3 (0.46) LPLLIPGTSHRMAPK1TDP1
SCHEMBL12967061 0.77 LMNA (0.57) L3MBTL1TP53LMNARXFP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed