SCHEMBL415478

SCHEMBL415478

CCc1ccc(Sc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.59
SLC6A4 P31645 1/20 0.57
LMNA P02545 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
HTR2C P28335 1/20 0.42
HTR6 P50406 1/20 0.42
KIF11 P52732 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
CHRNA7 P36544 1/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18159470 0.90 TP53 (0.48) TP53SLC6A4LMNARXFP1ALDH1A1
SCHEMBL576175 0.90 TP53 (0.48) TP53SLC6A4LMNARXFP1ALDH1A1
SCHEMBL16933906 0.83 EGFR (0.42) TP53SLC6A4LMNARXFP1ALDH1A1
SCHEMBL19938060 0.82 SLC6A4 (0.53) SLC6A4ALDH1A1HPGDMAOAMAOB
Diphenylsulfane SCHEMBL27384291 0.82 ALDH1A1 (0.50) TP53SLC6A4ALDH1A1HPGDMAOA
SCHEMBL382957 0.81 ALDH1A1 (0.53) TP53LMNARXFP1ALDH1A1HPGD
SCHEMBL15500070 0.81 MLYCD (0.42) TP53SLC6A4LMNARXFP1ALDH1A1
SCHEMBL24917160 0.80 SLC6A4 (0.55) SLC6A4ALDH1A1HPGDMAOAMAOB
Diphenylsulfane SCHEMBL7782824 0.79 SLC6A4 (0.48) TP53SLC6A4LMNARXFP1ALDH1A1
SCHEMBL12967061 0.79 LMNA (0.57) TP53LMNARXFP1ALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022258259-A1 NOVEL DIARYLIODONIUM SALT MIXTURES AS LOW MOLECULAR WEIGHT PHOTOINITIATORS WITH MINIMIZED CRYSTALLIZATION BEHAVIOR AND ELEVATED SOLUBILITY FEW CHEMICALS GMBH (DE) 2022-12-15 WO disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
EP-3562895-B1 CURABLE HIGH REFRACTIVE INDEX INK COMPOSITIONS AND ARTICLES PREPARED FROM THE INK COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2021-08-18 EP disclosed
EP-3372579-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2020-10-28 EP disclosed
EP-2915803-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2020-07-22 EP disclosed
EP-3536683-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2019-09-11 EP disclosed
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-05-28 US disclosed
US-10246536-B2 Functionalized highly syndiotactic polystyrene and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2019-04-02 US disclosed
EP-3372579-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2018-09-12 EP disclosed
US-10007183-B2 Compound for forming organic film, and organic film composition using the same, process for forming organic film, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-20090137611-A1 Fungicide N-Cyclopropyl-Sulfonylamide Derivatives BAYER CROPSCIENCE AG (DE) 2009-05-28 US disclosed
US-7358025-B2 Etching resistance; novolak resin having a fluorene or tetrahydrospirobiindene structure, an organic solvent, an acid generator, and a crosslinker, optionally combined with an intermediate layer having an antireflective effect SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-04-15 US disclosed
US-7303855-B2 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-12-04 US disclosed
US-20070275325-A1 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-11-29 US disclosed
US-20070225395-A1 Thermally stable cationic photocurable compositions WOLF JEAN-PIERRE 2007-09-27 US disclosed
EP-1588858-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-08-08 EP disclosed
EP-0844269-B1 BLOCK COPOLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS KATAOKA KAZUNORI (JP) 2002-10-23 EP disclosed
US-5929177-A LIVING POLYMER WITH HYDROPHILIC, HYDROPHOBIC SEGMENTS Kataoka, Kazunori (JP) 1999-07-27 US disclosed
EP-0844269-A1 BLOCK POLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS Kataoka, Kazunori (JP) 1998-05-27 EP disclosed
US-4124370-A Diphenyl ethers for tobacco sucker control ROHM AND HAAS COMPANY (US) 1978-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition PAH, ALKBH1, ALKBH3 TP53 3108/4885SLC6A4 3832/4885LMNA 1986/4885
US-10007183-B2 Compound for forming organic film, and organic film composition using the same, process for forming organic film, and patterning process OR10J3, RER1, OLA1 TP53 3605/4885SLC6A4 3085/4885LMNA 2005/4885
US-20090137611-A1 Fungicide N-Cyclopropyl-Sulfonylamide Derivatives CYP51A1, ERG28, CBR3 TP53 4222/4885SLC6A4 2653/4885LMNA 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.