Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610731 | 0.87 | AGTR2 (0.51) | AGTR2AGTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6604852 | 0.86 | AGTR2 (0.36) | AGTR2AGTR1ALDH1A1ELANEMEN1 | |
| SCHEMBL6607743 | 0.86 | HTT (0.41) | AGTR2AGTR1 | |
| SCHEMBL6605204 | 0.85 | AGTR1 (0.38) | AGTR2AGTR1 | |
| SCHEMBL8548644 | 0.81 | ALDH1A1 (0.36) | AGTR2AGTR1ALDH1A1KDM4ELMNA | |
| SCHEMBL8944447 | 0.81 | AGTR1 (0.36) | AGTR2AGTR1KDM4EMEN1KMT2A | |
| SCHEMBL6608525 | 0.79 | AGTR1 (0.44) | AGTR2AGTR1 | |
| SCHEMBL6606968 | 0.79 | AGTR1 (0.47) | AGTR2AGTR1 | |
| SCHEMBL6606053 | 0.78 | AGTR1 (0.50) | AGTR2AGTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6607142 | 0.77 | BRS3 (0.39) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |