Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944556 | 0.91 | GAA (0.45) | ALDH1A1KDM4EKMT2AADRA2AADRA1D | |
| SCHEMBL8944741 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EMEN1KMT2AADRA2A | |
| SCHEMBL8944628 | 0.81 | ADRA2A (0.41) | ALDH1A1LMNAMEN1KMT2AADRA2A | |
| SCHEMBL8944902 | 0.80 | CYP2A13 (0.39) | ALDH1A1KDM4ENISCH | |
| SCHEMBL8944681 | 0.80 | MAPK1 (0.43) | ALDH1A1KDM4EKMT2ANISCHMAPT | |
| SCHEMBL8944755 | 0.80 | LMNA (0.40) | LMNAKMT2ANISCH | |
| SCHEMBL8944697 | 0.78 | HTR1B (0.49) | ALDH1A1KDM4EMEN1KMT2ANISCH | |
| SCHEMBL8944841 | 0.77 | KDM4E (0.45) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL8944813 | 0.77 | NISCH (0.47) | NISCH | |
| SCHEMBL8944498 | 0.76 | TAAR1 (0.42) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| US-5492912-A | IMPROVES GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |