Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944530 | 0.82 | ALDH1A1 (0.46) | KDM4EMEN1KMT2AALDH1A1ADRA2A | |
| SCHEMBL8944697 | 0.81 | HTR1B (0.49) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8944556 | 0.80 | GAA (0.45) | KDM4EKMT2AALDH1A1SMN1; SMN2ADRA2A | |
| SCHEMBL8944813 | 0.79 | NISCH (0.47) | NISCH | |
| SCHEMBL8944702 | 0.78 | NISCH (0.42) | NISCH | |
| SCHEMBL8944625 | 0.73 | NISCH (0.41) | NISCH | |
| SCHEMBL8944498 | 0.72 | TAAR1 (0.42) | NISCH | |
| SCHEMBL8944628 | 0.72 | ADRA2A (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2ADRA2A | |
| SCHEMBL2387265 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1TDP1POLBNISCH | |
| SCHEMBL8944755 | 0.71 | LMNA (0.40) | KMT2ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| US-5492912-A | IMPROVES GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |