Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387265 | 0.94 | KDM4E (0.44) | KDM4ETDP1ALDH1A1POLBNISCH | |
| SCHEMBL8944853 | 0.82 | SIGMAR1 (0.44) | KDM4ETDP1ALDH1A1POLBNISCH | |
| SCHEMBL8944755 | 0.81 | LMNA (0.40) | KMT2ANISCH | |
| SCHEMBL8944625 | 0.80 | NISCH (0.41) | NISCHSIGMAR1 | |
| SCHEMBL8944840 | 0.80 | KDM4E (0.43) | KDM4ETDP1ALDH1A1POLBCCR4 | |
| SCHEMBL8944702 | 0.79 | NISCH (0.42) | NISCHSIGMAR1 | |
| SCHEMBL9036092 | 0.78 | KDM4E (0.45) | KDM4ETDP1ALDH1A1POLBKMT2A | |
| SCHEMBL8944902 | 0.77 | CYP2A13 (0.39) | KDM4EALDH1A1POLBNISCHCYP2A13 | |
| SCHEMBL2386441 | 0.75 | KDM4E (0.47) | KDM4ETDP1ALDH1A1POLBKMT2A | |
| SCHEMBL8944498 | 0.75 | TAAR1 (0.42) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| US-5492912-A | IMPROVES GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |