Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.56 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944832 | 0.93 | CTSS (0.47) | CTSSCTSLCTSBCTSDPSMB8 | |
| SCHEMBL8944991 | 0.86 | PSMB8 (0.47) | CTSBCTSDPSMB8PSMB11PSMA7 | |
| SCHEMBL8944695 | 0.84 | REN (0.45) | CTSD | |
| SCHEMBL8944865 | 0.81 | CTSL (0.50) | CTSSCTSLCTSBCTSD | |
| SCHEMBL8663687 | 0.78 | CTSD (0.47) | CTSSCTSLCTSBCTSDPSMB8 | |
| SCHEMBL8665786 | 0.77 | CTSD (0.48) | CTSLCTSDPSMB5 | |
| SCHEMBL8944981 | 0.76 | CTSD (0.48) | CTSLCTSBCTSDPSMB8PSMB1 | |
| SCHEMBL8664078 | 0.73 | CTSD (0.60) | CTSDPSMB5 | |
| SCHEMBL7408631 | 0.73 | CTSS (0.61) | CTSSCTSLCTSBTACR2POLB | |
| SCHEMBL7404835 | 0.73 | CTSS (0.61) | CTSSCTSLCTSBTACR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |