Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663687 | 0.93 | CTSD (0.47) | CTSDCTSBMMEECE1PSMB1 | |
| SCHEMBL8944865 | 0.92 | CTSL (0.50) | CTSDCTSBMMEECE1CTSK | |
| SCHEMBL8662047 | 0.88 | PSMB1 (0.54) | CTSBCAPN1PSMB1CTSKMMP3 | |
| SCHEMBL8664364 | 0.87 | CTSD (0.49) | CTSDCTSBCAPN1PSMB1CTSK | |
| SCHEMBL7295499 | 0.84 | CTSL (0.51) | CTSDCTSBMMEECE1PSMB1 | |
| SCHEMBL8661021 | 0.84 | SMN1; SMN2 (0.48) | CTSBMMEECE1CTSL | |
| SCHEMBL7305584 | 0.82 | CYP1A2 (0.53) | CTSBMMEECE1CAPN1CTSK | |
| SCHEMBL8660791 | 0.82 | CTRB1 (0.50) | CTSBCTSKCTSL | |
| SCHEMBL8669118 | 0.82 | CTSD (0.49) | CTSDCTSBMMEECE1CAPN1 | |
| SCHEMBL8944832 | 0.82 | CTSS (0.47) | CTSDCTSBPSMB1CTSKPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |