Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | PPM1G | O15355 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | PPM1A | P35813 | 1/20 | 0.39 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946290 | 0.86 | NQO2 (0.53) | ACHENQO2 | |
| SCHEMBL6251453 | 0.83 | GRM2 (0.39) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL1613356 | 0.82 | PTGES (0.38) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL8946246 | 0.81 | CYP1A2 (0.42) | NQO2 | |
| SCHEMBL17372698 | 0.78 | MARS1 (0.38) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL158714 | 0.78 | IGFBP3 (0.41) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL29384232 | 0.78 | IGFBP3 (0.41) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL9463397 | 0.78 | AKR1C4 (0.44) | PTGESPPM1GALOX5PTPN1KDM5A | |
| SCHEMBL8946339 | 0.78 | ESR1 (0.42) | NQO2 | |
| SCHEMBL8946957 | 0.78 | NQO2 (0.39) | NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493027-A | ANTIEPILEPTIC AGENTS, NEUROGENATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1994017042-A1 | ANTICONVULSIVE AGENTS AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-08-04 | — | — | WO | disclosed |