Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.44 |
| ▸ | PYGL | P06737 | 9/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946617 | 0.91 | L3MBTL1 (0.53) | L3MBTL1NTRK1PYGLNTRK3 | |
| SCHEMBL8946420 | 0.86 | L3MBTL1 (0.47) | L3MBTL1NTRK1PYGLNTRK3 | |
| SCHEMBL8946504 | 0.85 | L3MBTL1 (0.47) | L3MBTL1NTRK1PYGLNTRK3 | |
| SCHEMBL8946728 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NTRK1PYGLNTRK3MEN1 | |
| SCHEMBL8946618 | 0.82 | L3MBTL1 (0.51) | L3MBTL1NTRK1NTRK3KMT2A | |
| SCHEMBL8946576 | 0.82 | L3MBTL1 (0.51) | L3MBTL1NTRK1NTRK3KMT2A | |
| SCHEMBL8946920 | 0.81 | L3MBTL1 (0.50) | L3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL8946307 | 0.81 | L3MBTL1 (0.50) | L3MBTL1NTRK1PYGLNTRK3MEN1 | |
| SCHEMBL8946547 | 0.81 | L3MBTL1 (0.49) | L3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL8946654 | 0.80 | L3MBTL1 (0.55) | L3MBTL1NTRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |