Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946885 | 0.90 | DHODH (0.49) | L3MBTL1 | |
| SCHEMBL8946750 | 0.90 | L3MBTL1 (0.48) | SMN1; SMN2MEN1MAPTKMT2AHTT | |
| SCHEMBL8946920 | 0.85 | L3MBTL1 (0.50) | SMN1; SMN2MEN1MAPTKMT2AHTT | |
| SCHEMBL8946654 | 0.84 | L3MBTL1 (0.55) | SMN1; SMN2MEN1MAPTMAPK1KMT2A | |
| SCHEMBL8946535 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1MAPTMAPK1RECQL | |
| SCHEMBL8946735 | 0.82 | L3MBTL1 (0.51) | MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8946547 | 0.80 | L3MBTL1 (0.49) | MEN1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL8946858 | 0.80 | ADORA3 (0.53) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL8946728 | 0.80 | L3MBTL1 (0.51) | MEN1KMT2AHTTRAB9AL3MBTL1 | |
| SCHEMBL8946617 | 0.79 | L3MBTL1 (0.53) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |