Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170505 | 0.88 | TBXAS1 (0.42) | HDAC2HDAC1HDAC3HDAC6TBXAS1 | |
| SCHEMBL7364660 | 0.80 | ALDH1A1 (0.40) | HDAC2HDAC1HDAC3HDAC6CA1 | |
| SCHEMBL28054660 | 0.79 | POLB (0.40) | HDAC2HDAC1HDAC3MGLLHDAC8 | |
| SCHEMBL28462617 | 0.77 | SOAT2 (0.46) | LMNATSHRPTGS1 | |
| SCHEMBL8670732 | 0.76 | HDAC1 (0.47) | HDAC2HDAC1HDAC3HDAC6HDAC4 | |
| SCHEMBL5747628 | 0.76 | CA1 (0.47) | HDAC2HDAC1HDAC6TP53CA1 | |
| SCHEMBL8709577 | 0.73 | LSS (0.38) | HDAC2HDAC1HDAC3HDAC6TP53 | |
| SCHEMBL5540196 | 0.71 | HDAC2 (0.57) | HDAC2HDAC1MGLL | |
| SCHEMBL5534575 | 0.71 | HDAC2 (0.57) | HDAC2HDAC1MGLL | |
| SCHEMBL8709601 | 0.71 | GPR52 (0.49) | TP53CA1MGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567841-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-22 | — | — | US | disclosed |