Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948061 | 0.85 | SIGMAR1 (0.52) | HTR2AHTR2CCNR2HTR7HTR6 | |
| SCHEMBL8948024 | 0.85 | HTR2A (0.47) | HTR2AHTR2CDRD2CNR2HTR7 | |
| SCHEMBL8948001 | 0.84 | HTR2A (0.43) | HTR2AHTR2CDRD2CNR2HTR7 | |
| SCHEMBL8948051 | 0.79 | HTR2A (0.55) | HTR2AHTR2CDRD2HTR7HTR6 | |
| SCHEMBL8948150 | 0.79 | HTR2A (0.55) | HTR2AHTR2CDRD2CNR2HTR7 | |
| SCHEMBL8948058 | 0.77 | CNR2 (0.49) | HTR2AHTR2CDRD2CNR2HTR7 | |
| SCHEMBL8948000 | 0.75 | HTR2A (0.50) | HTR2AHTR2CDRD2HTR7HTR6 | |
| SCHEMBL8948034 | 0.75 | HTR2A (0.52) | HTR2AHTR2CDRD2CNR2HTR7 | |
| SCHEMBL8948192 | 0.75 | HTR1A (0.65) | HTR2AHTR2CHTR7GRM2 | |
| SCHEMBL8948121 | 0.74 | HTR2A (0.57) | HTR2AHTR2CDRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |