Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808531 | 0.84 | TSHR (0.54) | LTB4RLTB4R2LMNATSHRALDH1A1 | |
| SCHEMBL10743698 | 0.82 | PPARG (0.53) | LTB4RLTB4R2LMNA | |
| SCHEMBL6894976 | 0.82 | LMNA (0.51) | LTB4RLTB4R2LMNATSHRALDH1A1 | |
| SCHEMBL15110844 | 0.80 | LMNA (0.58) | LMNATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL6895558 | 0.77 | LMNA (0.51) | LTB4RLTB4R2LMNATSHRALDH1A1 | |
| SCHEMBL1840149 | 0.76 | LTB4R (0.47) | LTB4RLTB4R2 | |
| SCHEMBL9442052 | 0.76 | L3MBTL1 (0.52) | LMNAALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL6965435 | 0.76 | LMNA (0.55) | LMNAALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1629682 | 0.75 | ALDH1A1 (0.70) | LMNATSHRALDH1A1HTTKMT2A | |
| SCHEMBL29875722 | 0.75 | ALDH1A1 (0.70) | LMNATSHRALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |