Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 6/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553630 | 0.91 | CASP1 (0.64) | CTSLCASP1 | |
| SCHEMBL6159279 | 0.91 | CASP1 (0.64) | CTSLCASP1 | |
| SCHEMBL722757 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL7688519 | 0.91 | PSMB1 (0.57) | CTSLPSMB1CASP1MMEECE1 | |
| SCHEMBL1491365 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL3569541 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL8078067 | 0.90 | PSMB1 (0.56) | CTSLPSMB1CASP1MMEECE1 | |
| SCHEMBL7736831 | 0.89 | KYNU (0.60) | CTSLPSMB1CASP1MMEECE1 | |
| SCHEMBL5181237 | 0.89 | KYNU (0.60) | CTSLPSMB1CASP1MMEECE1 | |
| SCHEMBL14822417 | 0.87 | CASP1 (0.54) | CTSLCASP1CTSKTACR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559256-A | Aminediol protease inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1996-09-24 | — | — | US | disclosed |