SCHEMBL8957382

SCHEMBL8957382

CC(C)(C)OC(=O)CN(CC(=O)O)CC(Cc1ccc(O)cc1)N(CC(=O)O)CC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
OPRK1 P41145 5/20 0.36
OPRM1 P35372 7/20 0.35
OPRD1 P41143 4/20 0.35
MAOB P27338 3/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
NR1D1 P20393 3/20 0.34
SLC7A5 Q01650 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957471 0.95 CA1 (0.38) CTSSCTSKOPRK1OPRM1OPRD1
SCHEMBL5374479 0.88 CTSS (0.38) CTSSCTSKOPRK1OPRM1OPRD1
SCHEMBL8091529 0.87 CTSS (0.39) CTSSCTSKOPRK1OPRM1OPRD1
SCHEMBL8902337 0.84 NR1D1 (0.42) MAOBCA1CA2NR1D1
SCHEMBL21852438 0.81 MAOB (0.38) MAOBCA1CA2
SCHEMBL8090953 0.80 ATM (0.39) CTSSCTSKOPRK1OPRM1OPRD1
SCHEMBL8842200 0.79 OPRD1 (0.41) OPRK1OPRM1OPRD1CA1CA2
SCHEMBL8099592 0.78 SMN1; SMN2 (0.40) MAOBNR1D1
SCHEMBL3748687 0.78 NR1D1 (0.36) CTSSCTSKCA1CA2NR1D1
SCHEMBL8335482 0.78 ACACB (0.40) NR1D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482700-A Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast SCHERING AKTIENGESELLSCHAFT (DE) 1996-01-09 US disclosed