Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.65 |
| ▸ | GABRD | O14764 | 4/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.65 |
| ▸ | GABRE | P78334 | 4/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.60 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL21145282 | 1.00 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL21145284 | 1.00 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL1835366 | 0.90 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Maleic Acid SCHEMBL3118041 | 0.90 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL1835364 | 0.90 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL28768987 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL28068205 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL31016717 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Maleic Acid SCHEMBL4623286 | 0.86 | TSHR (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fumaric Acid SCHEMBL10400867 | 0.83 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120865671-A | SIS soap-free emulsion and preparation method and application thereof | 北京化工大学 | 2025-10-31 | — | — | CN | disclosed |
| EP-0690885-A1 | METHOD OF PRODUCTION OF COPOLYMERS OF POLYAMINO ACIDS | Calwood Chemical Industries, Inc. (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0690885-A4 | METHOD OF PRODUCTION OF COPOLYMERS OF POLYAMINO ACIDS | SRCHEM INC (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994021710-A1 | METHOD OF PRODUCTION OF COPOLYMERS OF POLYAMINO ACIDS | SRCHEM, INC. (US) | 1994-09-29 | — | — | WO | disclosed |
| US-5292858-A | Method of production of copolymers of polyamino acids | SRCHEM INCORPORATED (US) | 1994-03-08 | — | — | US | disclosed |