Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874596 | 0.88 | PPARG (0.53) | LMNAPPARGAGTR1AGTR2ENPP2 | |
| SCHEMBL9851425 | 0.84 | AGTR1 (0.56) | CYP19A1LMNAPPARGAGTR1AGTR2 | |
| SCHEMBL7095165 | 0.82 | LMNA (0.54) | LMNAAGTR1AGTR2ENPP2TP53 | |
| SCHEMBL8566073 | 0.75 | PPARG (0.61) | LMNAPPARGAGTR1AGTR2ENPP2 | |
| SCHEMBL9854319 | 0.74 | BRD4 (0.53) | LMNAPPARGAGTR1AGTR2TP53 | |
| SCHEMBL5573395 | 0.73 | CYP19A1 (0.51) | CYP19A1PPARGMEN1MAPTKMT2A | |
| SCHEMBL9853637 | 0.73 | PPARG (0.74) | LMNAPPARGAGTR1AGTR2ENPP2 | |
| SCHEMBL9851543 | 0.72 | AGTR1 (0.66) | LMNAPPARGAGTR1AGTR2ENPP2 | |
| SCHEMBL8876431 | 0.72 | AGTR1 (0.53) | LMNAAGTR1AGTR2ENPP2TP53 | |
| SCHEMBL9847866 | 0.70 | AGTR2 (0.56) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |