SCHEMBL8959018

SCHEMBL8959018

CCC(C)Oc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
MTNR1A P48039 4/20 0.45
MTNR1B P49286 3/20 0.45
ACACB O00763 2/20 0.44
PKM P14618 2/20 0.43
NPC1 O15118 1/20 0.43
EPHX2 P34913 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ABL1 P00519 4/20 0.42
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959129 0.90 KMT2A (0.49) KMT2AMEN1MTNR1AMTNR1BACACB
SCHEMBL8959019 0.89 HPGD (0.39) KMT2AMEN1MTNR1AMTNR1BACACB
SCHEMBL10385565 0.85 KMT2A (0.61) KMT2AMEN1MTNR1AMTNR1BACACB
SCHEMBL9503004 0.82 L3MBTL1 (0.44) KMT2AMEN1PKMNPC1RAB9A
SCHEMBL8959043 0.80 KMT2A (0.46) KMT2AMEN1PKMNPC1EPHX2
SCHEMBL8959189 0.80 PKM (0.56) KMT2AMEN1PKMNPC1EPHX2
SCHEMBL8959066 0.79 KMT2A (0.53) KMT2AMEN1MTNR1AACACBPKM
SCHEMBL8959169 0.79 NPC1 (0.52) KMT2AMEN1PKMNPC1EPHX2
SCHEMBL8959167 0.79 KMT2A (0.50) KMT2AMEN1MTNR1AMTNR1BPKM
SCHEMBL8959097 0.79 KMT2A (0.42) KMT2AMEN1PKMNPC1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed