SCHEMBL8959097

SCHEMBL8959097

CCC(C)COCc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MEN1 O00255 3/20 0.42
ATM Q13315 1/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 2/20 0.40
PDK2 Q15119 1/20 0.39
NPC1 O15118 5/20 0.39
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
PKM P14618 3/20 0.38
RAB9A P51151 2/20 0.38
CYP3A4 P08684 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959095 0.91 KMT2A (0.43) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8958965 0.87 KMT2A (0.48) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959043 0.83 KMT2A (0.46) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959018 0.79 KMT2A (0.48) KMT2AMEN1CNR1CNR2SMN1; SMN2
SCHEMBL8959072 0.78 CNR1 (0.57) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959129 0.77 KMT2A (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1NPC1
SCHEMBL8958937 0.76 CSNK2A1 (0.51) KMT2AMEN1ATMSMN1; SMN2PDK2
SCHEMBL8959057 0.76 LTA4H (0.52) KMT2AMEN1ATMSMN1; SMN2ALDH1A1
SCHEMBL8959189 0.70 PKM (0.56) KMT2AMEN1SMN1; SMN2NPC1PPARD
SCHEMBL8959066 0.69 KMT2A (0.53) KMT2AMEN1SMN1; SMN2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed