SCHEMBL8959043

SCHEMBL8959043

CCC(CC)Cc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 2/20 0.43
PKM P14618 2/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
CYP3A4 P08684 1/20 0.41
EPHX2 P34913 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
S1PR2 O95136 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
LPAR2 Q9HBW0 1/20 0.40
GAA P10253 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958965 0.83 KMT2A (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959097 0.83 KMT2A (0.42) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL9505094 0.82 SMN1; SMN2 (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959072 0.82 CNR1 (0.57) KMT2AMEN1SMN1; SMN2ALDH1A1CNR1
SCHEMBL8959095 0.81 KMT2A (0.43) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959018 0.80 KMT2A (0.48) KMT2AMEN1SMN1; SMN2PKMCNR1
SCHEMBL8959057 0.80 LTA4H (0.52) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959129 0.79 KMT2A (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959189 0.73 PKM (0.56) KMT2AMEN1SMN1; SMN2PKMEPHX2
SCHEMBL8959066 0.72 KMT2A (0.53) KMT2AMEN1SMN1; SMN2ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP claimed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US claimed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP claimed
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed