SCHEMBL8960512

SCHEMBL8960512

N[C@@H](Cc1c[nH]cn1)C(=O)NCCO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NLN Q9BYT8 3/20 0.37
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30401731 0.99 NLN (0.36) NLNMEN1USP2ALDH1A1MAPT
SCHEMBL14151247 0.93 NLN (0.39) NLN
SCHEMBL7624042 0.89 NLN (0.42) NLN
SCHEMBL3000079 0.89 NLN (0.37) NLN
SCHEMBL7624049 0.89 NLN (0.42) NLN
SCHEMBL13080959 0.87 DPP7 (0.38) NLN
SCHEMBL9847297 0.86 MME (0.37) NLN
Hydrochloric Acid SCHEMBL5263726 0.86 NLN (0.38) NLN
SCHEMBL8388715 0.86 GNAI3 (0.39) NLN
SCHEMBL18381248 0.86 MME (0.37) NLN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409517-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-12-12 US claimed
EP-4415561-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2024-08-21 EP claimed
WO-2023062110-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2023-04-20 WO claimed
US-20240409517-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-12-12 US disclosed
EP-4415561-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2024-08-21 EP disclosed
WO-2023062110-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2023-04-20 WO disclosed
US-20140155419-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. 2014-06-05 US disclosed
US-5519006-A Phosphonated arylethanolamine compounds with anti-hyperglycemic and/or anti-obesity activity SMITHKLINE BEECHAM PLC (GB) 1996-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409517-A1 ORGANIC COMPOUNDS HTR3C, HTR3A, H1-0 NLN 2675/4885MEN1 1452/4885USP2 4240/4885
US-20140155419-A1 COMPOUNDS AND METHODS RORC, RORB, RORA NLN 2757/4885MEN1 4672/4885USP2 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.