Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960660 | 0.87 | CYP1A2 (0.49) | CDC7DBF4PTGS2ALDH1A1KDM4E | |
| SCHEMBL9768642 | 0.79 | ALDH1A1 (0.62) | CDC7DBF4PTGS2ALDH1A1KDM4E | |
| SCHEMBL7852125 | 0.72 | ALDH1A1 (0.50) | PTGS2ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL11456658 | 0.71 | CDC7 (0.67) | CDC7DBF4PTGS2ALDH1A1KDM4E | |
| SCHEMBL21670773 | 0.71 | PTGS2 (0.56) | CDC7DBF4PTGS2ALDH1A1KDM4E | |
| SCHEMBL11287147 | 0.70 | PTGS2 (0.74) | PTGS2ALDH1A1KDM4EPTGDR2MAPT | |
| SCHEMBL9958269 | 0.70 | ALDH1A1 (0.51) | CDC7DBF4PTGS2ALDH1A1KDM4E | |
| SCHEMBL11284205 | 0.70 | KDM4E (0.58) | PTGS2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL11460695 | 0.70 | KDM4E (0.58) | PTGS2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL12245630 | 0.70 | ALOX5 (0.69) | PTGS2ALDH1A1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560136-B1 | Neuroprotective drug | KANEBO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5399571-A | Antihypoxic agents, brain disorders | KANEBO, LTD. (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0560136-A1 | Neuroprotective drug | KANEBO, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |