Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.67 |
| ▸ | DBF4 | Q9UBU7 | 8/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.63 |
| ▸ | CDK2 | P24941 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | TDO2 | P48775 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282345 | 0.91 | PTGS2 (0.68) | CDC7DBF4CCNE1CDK2PTGS2 | |
| SCHEMBL9768642 | 0.91 | ALDH1A1 (0.62) | CDC7DBF4CCNE1CDK2PTGS2 | |
| SCHEMBL7844433 | 0.85 | PTGS2 (0.80) | CDC7DBF4CCNE1CDK2PTGS2 | |
| SCHEMBL11466268 | 0.83 | ALOX5 (0.69) | CDC7DBF4PTGS2ALDH1A1CYP1A2 | |
| SCHEMBL21670773 | 0.82 | PTGS2 (0.56) | CDC7DBF4PTGS2MAPK14ALDH1A1 | |
| SCHEMBL513703 | 0.82 | AKT1 (0.54) | CDC7DBF4CCNE1CDK2 | |
| SCHEMBL16011062 | 0.81 | ALOX5 (0.50) | CDC7DBF4CCNE1CDK2PTGS2 | |
| SCHEMBL11287147 | 0.81 | PTGS2 (0.74) | PTGS2ALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL11460695 | 0.81 | KDM4E (0.58) | PTGS2ALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL544858 | 0.81 | CDC7 (0.61) | CDC7DBF4CCNE1CDK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |