Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962629 | 1.00 | HDAC2 (0.33) | HDAC2HTR2CHTR2BNR1H4NPC1 | |
| SCHEMBL9540776 | 0.94 | SLC6A3 (0.36) | HDAC2 | |
| SCHEMBL8963181 | 0.90 | FFAR4 (0.31) | NR1H4FFAR4 | |
| SCHEMBL8963174 | 0.90 | FFAR4 (0.31) | NR1H4FFAR4 | |
| SCHEMBL8962781 | 0.87 | NAAA (0.34) | HDAC2NR1H4FFAR4 | |
| SCHEMBL8962789 | 0.87 | NAAA (0.34) | HDAC2NR1H4FFAR4 | |
| SCHEMBL8962761 | 0.86 | PANK3 (0.35) | HDAC2PANK3 | |
| SCHEMBL8963228 | 0.84 | P2RY14 (0.35) | HDAC2NPC1RAB9ACYP3A4DGAT1 | |
| SCHEMBL8963237 | 0.84 | P2RY14 (0.35) | HDAC2NPC1RAB9ACYP3A4DGAT1 | |
| SCHEMBL8962846 | 0.83 | SLC6A3 (0.39) | HDAC2NPC1RAB9ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |