Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962781 | 1.00 | NAAA (0.34) | NAAAFAAHTLR7NR1H4GBA1 | |
| SCHEMBL8962629 | 0.87 | HDAC2 (0.33) | NR1H4HDAC2FFAR4 | |
| SCHEMBL8962633 | 0.87 | HDAC2 (0.33) | NR1H4HDAC2FFAR4 | |
| SCHEMBL8725535 | 0.86 | NAAA (0.35) | NAAAFAAHGBA1LCTUGCG | |
| SCHEMBL7024343 | 0.86 | NAAA (0.35) | NAAAFAAHGBA1LCTUGCG | |
| SCHEMBL8963181 | 0.85 | FFAR4 (0.31) | NR1H4FFAR4 | |
| SCHEMBL8963174 | 0.85 | FFAR4 (0.31) | NR1H4FFAR4 | |
| SCHEMBL8962824 | 0.82 | KDM1A (0.41) | NAAAFAAH | |
| SCHEMBL8962831 | 0.82 | KDM1A (0.41) | NAAAFAAH | |
| SCHEMBL9540776 | 0.82 | SLC6A3 (0.36) | HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |