Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768468 | 0.76 | CA1 (0.47) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL4827468 | 0.74 | RAPGEF4 (0.55) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL23699016 | 0.73 | CA1 (0.44) | LMNACA1CA2RAPGEF4L3MBTL1 | |
| SCHEMBL30877454 | 0.73 | RAPGEF4 (0.47) | LMNACA1CA2RAPGEF4L3MBTL1 | |
| SCHEMBL31451788 | 0.72 | ALDH1A1 (0.39) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL20746242 | 0.72 | L3MBTL1 (0.48) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL15232123 | 0.71 | SLC1A3 (0.41) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL15232127 | 0.71 | SLC1A3 (0.41) | LMNAGAACA1CA2RAPGEF4 | |
| SCHEMBL20488675 | 0.71 | PPARG (0.53) | LMNARAPGEF4L3MBTL1PKMALDH1A1 | |
| SCHEMBL9840582 | 0.71 | HTR6 (0.52) | CA1CA2L3MBTL1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8198847-A | — | — | None | — | — | JP | disclosed |
| JP-H08198847-A | TRISUBSTITUTED PYRROLE DERIVATIVE | SAGAMI CHEM RES CENTER | 1996-08-06 | — | — | JP | disclosed |