Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059235 | 0.76 | ALDH1A1 (0.51) | ADORA3ADORA2AADORA1LMNAALDH1A1 | |
| SCHEMBL14748615 | 0.74 | NR1H2 (0.55) | TSHRADORA3ADORA2AADORA1LMNA | |
| SCHEMBL16154002 | 0.74 | LMNA (0.60) | TSHRADORA3ADORA2AADORA1LMNA | |
| SCHEMBL5983555 | 0.69 | MMP8 (0.57) | TSHRLMNAGAAKMT2A | |
| SCHEMBL10756249 | 0.69 | MMP8 (0.57) | TSHRLMNAGAAKMT2A | |
| SCHEMBL304815 | 0.69 | MMP8 (0.57) | TSHRLMNAGAAKMT2A | |
| SCHEMBL16746841 | 0.69 | CTSK (0.51) | TSHRALDH1A1GAAKMT2AMAPK1 | |
| SCHEMBL2392888 | 0.68 | LMNA (0.46) | TSHRLMNAALDH1A1GAAHPGD | |
| SCHEMBL8429965 | 0.68 | KMT2A (0.46) | TSHRLMNAALDH1A1GAAHPGD | |
| SCHEMBL27475261 | 0.68 | PIN1 (0.68) | TSHRLMNAALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489602-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |