Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963637 | 0.94 | MAPK13 (0.37) | OPRD1OPRM1CHEK2HTR2BHTR1A | |
| SCHEMBL8963516 | 0.94 | CHEK2 (0.42) | OPRD1OPRM1CHEK2HTR2BHTR1A | |
| SCHEMBL8963580 | 0.94 | PRMT5 (0.40) | OPRD1PRMT5TNKSPARP1TNKS2 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.93 | PRMT5 (0.40) | OPRD1PRMT5TNKSPARP1TNKS2 | |
| SCHEMBL8963737 | 0.92 | OPRM1 (0.38) | OPRD1OPRM1HTR2BHTR1AHTR1D | |
| SCHEMBL8963820 | 0.92 | HDAC6 (0.34) | OPRD1OPRM1CHEK2TNKSTNKS2 | |
| SCHEMBL8963675 | 0.89 | TACR1 (0.36) | OPRD1OPRM1CHEK2HTR2BHTR1A | |
| SCHEMBL8963679 | 0.88 | MEN1 (0.42) | OPRD1PRMT5MEN1KMT2ADRD2 | |
| SCHEMBL8964138 | 0.86 | SLC6A4 (0.38) | OPRD1OPRM1CHEK2HTR2BHTR1A | |
| SCHEMBL8963855 | 0.85 | TNKS (0.34) | CHEK2HTR2BHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |