Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963820 | 0.92 | HDAC6 (0.34) | OPRD1HDAC6TNKSTNKS2GNRHR | |
| SCHEMBL8963679 | 0.90 | MEN1 (0.42) | OPRD1PRMT5MEN1KMT2ASLC6A4 | |
| SCHEMBL8963580 | 0.89 | PRMT5 (0.40) | OPRD1TNKSTNKS2PRMT5TACR1 | |
| SCHEMBL8964174 | 0.89 | TACR1 (0.38) | OPRD1PRMT5TACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8963783 | 0.88 | PRMT5 (0.40) | OPRD1TNKSTNKS2PRMT5TACR1 | |
| SCHEMBL8963650 | 0.87 | CHEK2 (0.40) | OPRD1TNKSTNKS2PRMT5MEN1 | |
| SCHEMBL8963691 | 0.86 | TACR1 (0.34) | OPRD1HDAC6PRMT5TACR1GNRHR | |
| Hydrochloric Acid SCHEMBL8963518 | 0.86 | OPRD1 (0.41) | OPRD1HDAC6TNKSTNKS2PRMT5 | |
| SCHEMBL8964068 | 0.85 | PRMT5 (0.44) | OPRD1TNKSTNKS2PRMT5MEN1 | |
| SCHEMBL8964088 | 0.83 | OPRD1 (0.37) | OPRD1TNKSTNKS2PRMT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |