Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963792 | 0.91 | PIN1 (0.47) | TACR1PIN1SLC6A4MEN1KMT2A | |
| SCHEMBL8963467 | 0.89 | OPRD1 (0.41) | TACR1OPRD1SLC6A4KCNA5KCNH2 | |
| SCHEMBL8963860 | 0.88 | PIN1 (0.43) | TACR1PIN1SLC6A4MEN1KMT2A | |
| SCHEMBL8963679 | 0.88 | MEN1 (0.42) | OPRD1PIN1SLC6A4MEN1KMT2A | |
| SCHEMBL8963691 | 0.87 | TACR1 (0.34) | TACR1OPRD1SLC6A4KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL8963922 | 0.87 | OPRD1 (0.37) | TACR1OPRD1PIN1SLC6A4KCNA5 | |
| SCHEMBL8963787 | 0.86 | PIN1 (0.45) | TACR1PIN1SLC6A4MEN1KMT2A | |
| SCHEMBL8963561 | 0.84 | SLC6A2 (0.47) | OPRD1PIN1SLC6A4SLC6A2MAPK13 | |
| SCHEMBL8963580 | 0.82 | PRMT5 (0.40) | TACR1OPRD1SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8963344 | 0.82 | MAOA (0.37) | OPRD1PIN1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |