Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581325 | 0.83 | ALDH1A1 (0.51) | ALDH1A1GLS | |
| SCHEMBL29217261 | 0.82 | CASP3 (0.50) | ALDH1A1GLSMAOBMAPTNPSR1 | |
| SCHEMBL1264927 | 0.79 | ALOX15 (0.49) | ALDH1A1ALOX15NFE2L2PKMMAPT | |
| SCHEMBL1264929 | 0.79 | ALOX15 (0.49) | ALDH1A1ALOX15NFE2L2PKMMAPT | |
| SCHEMBL19205460 | 0.79 | NFE2L2 (0.38) | ALDH1A1ALOX15NFE2L2MMP9 | |
| SCHEMBL12134382 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GLSPKMMAOBMAPT | |
| SCHEMBL19205403 | 0.78 | TERT (0.40) | ALDH1A1ALOX15NFE2L2MMP9 | |
| SCHEMBL4578721 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GLSMAOBMAPTNPSR1 | |
| SCHEMBL12203853 | 0.77 | ALDH1A1 (0.54) | ALDH1A1GLSMAOBMAPTNPSR1 | |
| SCHEMBL19205475 | 0.76 | TERT (0.38) | ALDH1A1ALOX15NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523430-A | Protein farnesyl transferase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-04 | — | — | US | disclosed |