Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866493 | 0.83 | CA12 (0.49) | ALDH1A1GLSKMT2AMEN1CA12 | |
| SCHEMBL8967575 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLS | |
| SCHEMBL8533004 | 0.82 | GLS (0.50) | GLSKMT2ACHRM2MEN1CYP1A2 | |
| SCHEMBL4017572 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GLSKMT2AMEN1CA12 | |
| SCHEMBL9207150 | 0.79 | GLS (0.55) | GLSKMT2ACHRM2MEN1CYP1A2 | |
| SCHEMBL9330325 | 0.79 | MAPT (0.52) | ALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9330335 | 0.79 | MAPT (0.52) | ALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22121427 | 0.79 | GLS (0.59) | GLSCYP1A2CYP2C19 | |
| SCHEMBL17044807 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GLSKMT2AMEN1CA12 | |
| SCHEMBL16465525 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GLSKMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399460-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2008-07-15 | — | — | US | disclosed |
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-04-05 | — | — | US | disclosed |
| US-7186397-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO SUISSE SA (CH) | 2001-06-21 | — | — | US | disclosed |
| US-6221334-B1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO RESEARCH USA, INC. | 2001-04-24 | — | — | US | disclosed |
| EP-1077729-A2 | METAL COMPLEXES DERIVATIZED WITH FOLATE FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2001-02-28 | — | — | EP | disclosed |
| US-6093382-A | A FOLATE-RECEPTOR BINDING LIGAND COMPRSING ONE OR MORE FOLATE BINDING GROUPS, ATLEAST ONE OF WHICH IS CONJUGATED THROUGH ALPHA CARBOXYLATE VIA A LINKING GROUP TO MACROCYCLIC OR NON MACROCYCLIC METAL CHELATING LIGAND RADICAL | BRACCO RESEARCH USA INC. (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999059640-A2 | METAL COMPLEXES DERIVATIZED WITH FOLATE FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | FOLR1, FOLR2, SLC46A1 | ALDH1A1 782/4885GLS 191/4885KMT2A 2417/4885 |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | FOLR1, FOLR2, SLC46A1 | ALDH1A1 1176/4885GLS 166/4885KMT2A 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.