Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969750 | 0.81 | MAOA (0.37) | MAOAACHESMN1; SMN2 | |
| SCHEMBL8969680 | 0.80 | ALDH1A1 (0.33) | ACHEALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL8968480 | 0.79 | ALDH1A1 (0.41) | MAOAACHEALDH1A1KDM4ENPC1 | |
| SCHEMBL8968293 | 0.78 | — | — | |
| SCHEMBL8969448 | 0.73 | ACHE (0.37) | MAOAACHEALDH1A1KDM4ENPC1 | |
| SCHEMBL8970053 | 0.71 | ACHE (0.38) | ACHENPC1 | |
| SCHEMBL8969422 | 0.70 | HRH4 (0.34) | ACHE | |
| SCHEMBL8969986 | 0.68 | MAOA (0.35) | MAOAACHEALDH1A1KDM4ENPC1 | |
| SCHEMBL8968897 | 0.67 | BCHE (0.31) | ACHE | |
| SCHEMBL8969797 | 0.67 | LRRK2 (0.39) | ACHEALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |