Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 13/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970375 | 0.84 | ACHE (0.46) | ACHE | |
| SCHEMBL8969750 | 0.82 | MAOA (0.37) | ACHESMN1; SMN2LMNAMAOA | |
| SCHEMBL8969680 | 0.81 | ALDH1A1 (0.33) | ALDH1A1ACHEKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8968360 | 0.79 | MAOA (0.37) | ALDH1A1ACHEKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8969894 | 0.78 | KDM4E (0.38) | ALDH1A1ACHEKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8969797 | 0.74 | LRRK2 (0.39) | ALDH1A1ACHEKDM4ENPC1RAB9A | |
| SCHEMBL8968997 | 0.74 | CASP3 (0.34) | ALDH1A1ACHEMAPTBCHECYP2D6 | |
| SCHEMBL8968811 | 0.71 | LRRK2 (0.38) | HRH3 | |
| SCHEMBL8969246 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1MAPT | |
| SCHEMBL8968456 | 0.71 | ACHE (0.37) | ALDH1A1ACHEKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |