Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675062 | 0.78 | ALDH1A1 (0.44) | PPARAPPARGALDH1A1SLC6A4MTNR1A | |
| SCHEMBL8969144 | 0.78 | KDM4E (0.36) | MEN1KMT2ASMN1; SMN2PPARAPPARG | |
| SCHEMBL8419889 | 0.75 | LMNA (0.47) | MEN1KMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL29208313 | 0.71 | CA4 (0.41) | PPARAPPARGPKMALDH1A1CYP1A2 | |
| SCHEMBL8418493 | 0.69 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2KDM4EPKM | |
| SCHEMBL6040933 | 0.68 | LTA4H (0.38) | PPARAPPARGALDH1A1SLC6A4MTNR1A | |
| SCHEMBL16406607 | 0.67 | KMT2A (0.44) | MEN1KMT2APPARAPPARGALDH1A1 | |
| Acrylic Acid SCHEMBL29368977 | 0.66 | THRB (0.44) | MEN1KMT2ASMN1; SMN2PPARAPPARG | |
| SCHEMBL27623098 | 0.65 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2KDM4EPKM | |
| SCHEMBL1412775 | 0.65 | ALDH1A1 (0.50) | PPARAPPARGALDH1A1CYP2D6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |