Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 10/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968679 | 0.92 | CTSD (0.47) | CTSDACHEHTR2AHTR2CHTR2B | |
| SCHEMBL8969504 | 0.89 | ACHE (0.40) | CTSDACHEHTR2AHTR2CHTR2B | |
| SCHEMBL8969263 | 0.83 | CTSD (0.33) | CTSDHTR2AHTR2CHTR2B | |
| SCHEMBL8969466 | 0.83 | CTSD (0.49) | CTSDACHEHTR2AHTR2CHTR2B | |
| SCHEMBL8970140 | 0.83 | CTSD (0.32) | CTSD | |
| SCHEMBL8968949 | 0.80 | OPRM1 (0.31) | CTSD | |
| SCHEMBL8969006 | 0.80 | CTSD (0.52) | CTSDHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8969131 | 0.79 | HRH3 (0.31) | CTSDHRH3 | |
| SCHEMBL8968239 | 0.78 | — | — | |
| SCHEMBL8969419 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |