Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969460 | 0.84 | ACHE (0.42) | ACHE | |
| SCHEMBL8969797 | 0.84 | LRRK2 (0.39) | ACHE | |
| SCHEMBL8968456 | 0.80 | ACHE (0.37) | ACHE | |
| SCHEMBL8969894 | 0.80 | KDM4E (0.38) | ACHE | |
| SCHEMBL8969661 | 0.80 | BCHE (0.34) | ACHE | |
| SCHEMBL8969750 | 0.79 | MAOA (0.37) | ACHE | |
| SCHEMBL8968897 | 0.78 | BCHE (0.31) | ACHE | |
| SCHEMBL8970437 | 0.78 | MPO (0.36) | ACHE | |
| SCHEMBL8968997 | 0.78 | CASP3 (0.34) | ACHE | |
| SCHEMBL8969011 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |